MABS817MI
MilliporeSigma™ Mouse anti-AGT, Clone: 1B1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS817MI-Each-of-1 | In Stock | ₹ 45,464.76 |
MABS817MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,464.76
GST (18%): ₹ 8,183.657
Total Price: ₹ 53,648.417
Antigen
AGT
Classification
Monoclonal
Formulation
Mouse monoclonal IgG2 bascitic fluid containing 0.03% sodium azide.
Gene Symbols
AGT; SERPINA8
Immunogen
Purified recombinant fragment of human AGT expressed inE. coli.
Quantity
100 μL
Research Discipline
Signaling
Target Species
Human
Form
Ascites
Applications
Western Blot
Clone
1B1
Gene Accession No.
P01019
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype
IgG2b
Related Products
Description
- Specifically detects AGT clone: 1B1 in Human samples, and it is validated for Western Blotting Angiotensinogen (AGT) is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure
- The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II
- The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia
- Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development
- Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.