MABT825
MilliporeSigma™ Mouse anti-beta-Actin, Clone: 4C2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT825-Each-of-1 | In Stock | ₹ 42,114.80 |
MABT825 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,114.80
GST (18%): ₹ 7,580.664
Total Price: ₹ 49,695.464
Antigen
beta-Actin
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ACTB
Immunogen
KLH-conjugated linear peptide corresponding to the the N-terminal sequence of human beta-Actin.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001092.1
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunocytochemistry, Western Blot
Clone
4C2
Gene Accession No.
P60709
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Chicken, Human, Mouse, Rat
Form
Purified
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Description
- Specifically detects beta-Actin clone: 4C2 in Chicken, Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Western Blotting Actin, cytoplasmic 1 (UniProt P60709; also known as Beta-actin) is encoded by the ACTB gene (Gene ID 60) in human
- Actins are globular multi-functional proteins that serve as the basic building blocks of cytoskeletal microfilaments and are among the most conserved eukaryotic proteins
- Six actin types exist, skeletal muscle alpha-actin is encoded by the ACTA1 gene, smooth muscle alpha-actin by the ACTA2 gene, cytoplasmic beta-actin by the ACTB gene, cardiac muscle alpha-actin by the ACTC1 gene, cytoplasmic gamma-actin by the ACTG1 gene, and smooth muscle gamma-actin by the ACTG2 (a.k.a
- ACTA3) gene
- Although actins show 90% overall sequence homology, isoforms do show spatial, temporal, and tissue-specific expression patterns and only 50-60% homology is found in their 18 N-terminal residues
- Cytoplasmic β and γ-actins, are thought to be present in all cells, while the other four actin isoforms are typically found in specific adult muscle tissue types
- Actins exist in a variety of structural states, depending on the specific ionic conditions or the interaction with ligand proteins
- The oligomeric and polymeric forms that actin molecules assume are dependent on the distinct conformations they adopt.