MS106PABX
Epredia™ Lab Vision™ PCNA (Proliferating Cell Nuclear Antigen) Ab-1 Mouse Monoclonal Antibody, 20μg/mL, biotinylated, BSA and azide
Manufacturer: Fischer Scientific
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Antigen
PCNA (Proliferating Cell Nuclear Antigen) Ab-1
Classification
Monoclonal
Concentration
1mg/mL
Host Species
Mouse
Quantity
200 μL
Research Discipline
Cell Cycle
Target Species
Human, Insect, Mouse, Rat, Yeast
Isotype
IgG2a κ
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
PC10
Conjugate
Unconjugated
Immunogen
Recombinant rat PCNA protein
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- Expression of proliferating cell nuclear antigen (PCNA) or cyclin or polymerase δ auxiliary protein is elevated in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and M phases
- Its level correlates directly with rates of cellular proliferation and DNA synthesis
- PCNA/cyclin may act as an auxiliary protein of DNA polymerase-δ to play a fundamental role in the initiation of cell proliferation Host Species: Mouse Clone: PC10 Isotype: IgG2a/κ Species Reactivity: Human, Mouse, Rat, Insect, and Yeast
- Others not known
- Epitope: Not determined Immunogen: Recombinant rat PCNA protein Molecular Weight: 36kDa Positive Control: Raji cells; Tonsil, lymph node, or small intestine Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native and denatured) Flow Cytometry Note: USA: RUO; Int'l: RUO