MS1302P1ABX
CD47 Ab-2 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
CD47 Ab-2
Classification
Monoclonal
Concentration
1mg/mL
Host Species
Mouse
Quantity
100 μL
Research Discipline
Hematopoietic
Target Species
Human
Isotype
IgG2a κ
Applications
Immunofluorescence, Immunoprecipitation, Western Blot
Clone
B6H12.2
Conjugate
Unconjugated
Immunogen
Intact CD47 purified from placenta
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- CD47 antigen, also known as integrin associated-protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes
- It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines
- CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells
- Host Species: Mouse Clone: B6H12.2 Isotype: IgG1/κ Species Reactivity: Human
- Others not known
- Epitope: Ig domain Immunogen: Intact CD47 purified from placenta Molecular Weight: 47-52 kDa (reduced) and 45-50.5, 110 kDa (nonreduced) Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunofluorescence (Methanol fixed only) Immunoprecipitation (Native only) Flow Cytometry Blocks binding of SIRPα Inhibits in assays in which CD47-integrin association is required Note: USA: RUO; Int'l: RUO