MS130P

CDw75 Ab-1 Mouse Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

CDw75 Ab-1

Classification

Monoclonal

Concentration

200μg/mL

Host Species

Mouse

Quantity

1 mL

Research Discipline

B-Cell

Target Species

Human

Isotype

IgM κ

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

LN1

Conjugate

Unconjugated

Immunogen

Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Concentrated

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Description

  • CDw75 is a neuraminidase-sensitive sialoprotein, present on cell membrane and cytoplasm of germinal center B-cells and derived lymphomas
  • LN1 reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin's disease
  • LN1 is shown to be a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues
  • Host Species: Mouse Clone: LN1 Isotype: IgM/κ Species Reactivity: Human
  • Does not react with rat
  • Others not known Epitope: Not determined Immunogen: Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes Molecular Weight: 53 and 87 kDa Positive Control: Lymph node or tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence Flow Cytometry