MS1768R1

Epredia™ Lab Vision™ Tartrate Resistant Acid Phosphatase (TRAP) Ab-1, Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Tartrate Resistant Acid Phosphatase (TRAP) Ab-1

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Recombinant protein corresponding to N-terminal region of human TRAP

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Prediluted

Applications

Immunohistochemistry (Paraffin)

Clone

26E5

Host Species

Mouse

Quantity

1 mL

Research Discipline

Cancer and Tumor Biology

Target Species

Human

Isotype

IgG2b

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Description

  • Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase
  • It is detected in human alveolar macrophages, osteoclasts, spleen and liver
  • Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover
  • Host Species: Mouse Clone: 26E5 Isotype: IgG2b Species Reactivity: Human
  • Others not known
  • Epitope: N-terminal Immunogen: Recombinant protein corresponding to N-terminal region of human TRAP Positive Control: Lung (macrophages) Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)