MS369R1
DNA-PKcs Ab-1 Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
DNA-PKcs Ab-1
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
1 mL
Research Discipline
DNA Repair
Target Species
Human, Rat
Isotype
IgG1
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
18-2
Formulation
Ready-to-use for IHC (UVLP)
Immunogen
Human DNA-dependent Protein Kinase purified from HeLa cells
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Prediluted
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Description
- DNA-dependent Protein Kinase (DNA-PKcs) phosphorylates transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro
- In vivo, it is involved in repairing double strand DNA breaks
- Host Species: Mouse Clone: 18-2 Isotype: IgG1 Species Reactivity: Human and Rat
- Others not known
- Epitope: aa 1-2713 Immunogen: Human DNA-dependent Protein Kinase purified from HeLa cells Molecular Weight: 460 kDa Positive Control: LS174T cells, Tonsil Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence Immunoprecipitation (Native and denatured) Inhibits (50%) DNA-dependent Phosphorylation Note: USA: RUO; Int'l: RUO