MS382P1ABX
Chromogranin A Ab-3 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
Chromogranin A Ab-3
Classification
Monoclonal
Concentration
1mg/mL
Host Species
Mouse
Quantity
100 μL
Research Discipline
Oncogenesis
Target Species
Human, Non-human Primate
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin)
Clone
LK2H10 + PHE5
Conjugate
Unconjugated
Immunogen
Human pheochromocytoma
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- Chromogranin A (a protein of 439-amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets
- It is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors
- Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms
- Ab-3 cocktail is especially designed for sensitive detection of Chromogranin A in formalin-fixed, paraffin-embedded tissues
- Host Species: Mouse Clone: LK2H10 + PHE5 Isotype: IgG1 + IgG1 Species Reactivity: Human and Monkey
- Others not known
- Immunogen: Human pheochromocytoma Molecular Weight: 68-75 kDa Positive Control: Pancreas Cellular Localization: Cytoplasmic in endocrine cells Recommended for: Immunohistochemistry (Formalin/paraffin) Note: USA: RUO; Int'l: RUO