MS489S1

Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MS489S1-Each-of-1 In Stock ₹ 46,725.00

MS489S1 - Each of 1

₹ 46,725.00

In Stock

Quantity

1

Base Price: ₹ 46,725.00

GST (18%): ₹ 8,410.50

Total Price: ₹ 55,135.50

Antigen

Cytokeratin 17 Ab-1

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Keratin preparation from rat enterocytes

Quantity

500 μL

Research Discipline

Cytoskeletal Protein

Target Species

Human, Rat

Isotype

IgG2b κ

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

E3

Host Species

Mouse

Purification Method

Squamous cell CA, skin

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Concentrated

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Description

  • The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life
  • Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin
  • Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells
  • Host Species: Mouse Clone: E3 Isotype: IgG2b/κ Species Reactivity: Human and Rat
  • Others not known
  • Epitope: Not determined Immunogen: Cytokeratin preparation from rat enterocytes Molecular Weight: 46 kDa Positive Control: Squamous cell CA, Skin Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence