MS600P1ABX
HER-2/c-erbB-2/neu Ab-16 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
HER-2/c-erbB-2/neu Ab-16
Classification
Monoclonal
Concentration
1mg/mL
Host Species
Mouse
Quantity
100 μL
Research Discipline
EGFR Family
Target Species
Human
Isotype
IgG2a κ
Applications
Immunoprecipitation
Clone
L26
Conjugate
Unconjugated
Immunogen
Extracellular domain of recombinant human c-erbB-2/HER-2 oncoprotein
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
Related Products
Description
- c-erbB-2 is a receptor tyrosine kinase of the c-erbB family
- Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein Host Species: Mouse Clone: L26 Isotype: IgG1/κ Species Reactivity: Human
- Others not tested
- Epitope: Involved in the formation of heterodimers Immunogen: Extracellular domain of recombinant human HER-2/c-erbB-2 oncoprotein Molecular Weight: 185kDa Positive Control: SKBR-3 cells Cellular Localization: Membrane Recommended for: Immunohistochemistry (Not suitable) Western Blotting (Not suitable) Immunoprecipitation (Native only) Inhibits Binding of EGF (∽70%), NDF (∽40%) Reduces Affinity of EGF (3-fold) and NDF (2-fold) Note: USA: RUO; Int'l: RUO