MS770B0
L1 Cell Adhesion Molecule Ab-1 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
L1 Cell Adhesion Molecule Ab-1
Classification
Monoclonal
Concentration
200μg/mL
Host Species
Mouse
Quantity
100 μL
Research Discipline
Cancer and Tumor Biology
Target Species
Human
Isotype
IgG2a κ
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
UJ127
Conjugate
Biotin
Immunogen
Homogenous suspension of 16 week human fetal brain
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- Description The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia)
- The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation
- Expression of L1 protein is restricted to tissues arising from neuroectoderm
- Host Species: Mouse Clone: UJ127 Isotype: IgG1/k Species Reactivity: Human
- Others not known
- Epitope: Not determined Immunogen: Homogenous suspension of 16-week human fetal brain Molecular Weight: 220-240kDa Positive Control: IMR-5 cells Neuroblastoma Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native and denatured) Note: USA: RUO; Int'l: RUO