MS816PABX

MMP-9 (92kDa Collagenase IV) Ab-4 Mouse Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

MMP-9 (92kDa Collagenase IV) Ab-4

Classification

Monoclonal

Concentration

1mg/mL

Host Species

Mouse

Quantity

200 μL

Research Discipline

Proteases And Inhibitors

Target Species

Human

Isotype

IgG2a κ

Applications

Immunofluorescence

Clone

IA5

Conjugate

Unconjugated

Immunogen

Human native 92kDa MMP-9

Regulatory Status

RUO

Primary or Secondary

Primary

Form

Concentrated

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Description

  • MMPs are a group of enzymes involved in matrix degradation
  • They share some important characteristics, such as a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and inhibition by specific proteinase inhibitors known as tissue inhibitors of metalloproteinases (TIMPs)
  • Reportedly, MMPs play a crucial role in tumor cell invasion and metastasis
  • Host Species: Mouse Clone: IA5 Isotype: IgG1/κ Species Reactivity: Human
  • Others not known
  • Epitope: Not determined Immunogen: Human native 92kDa MMP-9 Molecular Weight: 92kDa (proform) and ∽86kDa (active form) Positive Control: Conditioned, serum-free medium from (TPA-treated) human fibrosarcoma HT-1080 cells Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Not suitable) Western Blotting Immunofluorescence Immunoprecipitation (Not suitable) Note: USA: RUO; Int'l: RUO