MHC class II (I-A/I-E) Antibody (M5/114.15.2), PE/Cy7, Novus Biologicals™

MHC class II (I-A/I-E)

Monoclonal

PE-Cyanine7

PBS with 0.05% Sodium Azide

H2-Ea-ps

The immunogen for this antibody was MHC Class II.

0.1 mL

Primary

The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

M5/114.15.2

Flow Cytometry

class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM

Rat

Protein A or G purified

Adaptive Immunity, Asthma, B Cell Development and Differentiation Markers, Cell Biology, Diabetes Research, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators

100504404

Human, Mouse

IgG2b κ