Myeloid Cell Marker Antibody (BM-1), PE/Atto594, Novus Biologicals™

Myeloid Cell Marker

Monoclonal

PE/ATTO 594

PBS with 0.05% Sodium Azide

Mouse

Protein A or G purified

Primary

Human

IgG1 κ

Flow Cytometry

BM-1

Flow Cytometry

myeloid specific antigen, myeloid specific protein, p183 DNA-binding cytoplasmic ptotein

Human peripheral blood mononuclear cells

0.1 mL

Recognizes 183kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This monoclonal antibody reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Store at 4°C in the dark. Do not freeze.