CD45RB Antibody (BRA-11 (same as BRA-11G)), PE/Atto594, Novus Biologicals™

CD45RB

Monoclonal

PE/ATTO 594

PBS with 0.05% Sodium Azide

PTPRC

Non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V)

0.1 mL

Primary

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

BRA-11 (same as BRA-11G)

Flow Cytometry

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Mouse

Protein A or G purified

Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Microglia Markers, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

5788.0

Human, Monkey (Negative), Rat (Negative)

IgG1 κ