VCAM-1/CD106 Antibody (B-K9), PE/Cy5.5, Novus Biologicals™

VCAM-1/CD106

Monoclonal

PE-Cyanine5.5

PBS with 0.05% Sodium Azide

VCAM1

Activated human umbilical vein endothelial cells (HUVEC)

0.1 mL

Primary

Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This monoclonal antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

B-K9

Flow Cytometry

CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1

Mouse

Protein A or G purified

Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers

7412.0

Human, Rat

IgG1 κ