MUC1 Antibody (rMUC1/960), PE/Cy5.5, Novus Biologicals™

MUC1

Monoclonal

PE-Cyanine5.5

PBS with 0.05% Sodium Azide

MUC1

Recombinant human MUC1 protein (Uniprot: P15941 )

0.1 mL

Primary

This monoclonal antibody reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this monoclonal antibody involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

rMUC1/960

Flow Cytometry

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Mouse

Protein A or G purified

Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

4582.0

Human

IgG2b κ