CD34 Antibody (HPCA1/1806R), PE/Cy7, Novus Biologicals™

CD34

Monoclonal

PE-Cyanine7

PBS with 0.05% Sodium Azide

CD34

Recombinant full-length human CD34 protein (Uniprot: P28906)

0.1 mL

Primary

This antibody recognizes a transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

HPCA1/1806R

Flow Cytometry

CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Rabbit

Protein A or G purified

Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

947.0

Human, Rat

IgG