Enolase 2/Neuron-specific Enolase Antibody (ENO2/1375), PE/Cy5.5, Novus Biologicals™

Enolase 2/Neuron-specific Enolase

Monoclonal

PE-Cyanine5.5

PBS with 0.05% Sodium Azide

ENO2

A synthetic peptide of human Enolase 2/Neuron-specific Enolase (around aa416-433) (exact sequence is proprietary) (Uniprot: P09104)

0.1 mL

Primary

Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

ENO2/1375

Flow Cytometry, Flow (Intracellular)

2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, EC 4.2.1.11, Enolase 2, enolase 2 (gamma, neuronal), gamma-enolase, Neural enolase, neuron specific gamma enolase, neurone-specific enolase, Neuron-specific enolase, NSE

Mouse

Protein A or G purified

Cancer, Cellular Markers, Neuronal Cell Markers, Neuroscience

2026.0

Human, Mouse, Rat

IgG2b κ