NA8150UG
MilliporeSigma™ anti-5-Methylcytosine Clone: 162 33 D3,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NA8150UG-Each-of-1 | In Stock | ₹ 42,968.31 |
NA8150UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,968.31
GST (18%): ₹ 7,734.296
Total Price: ₹ 50,702.606
Antigen
5-Methylcytosine
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Multi-species
Form
Purified
Applications
ELISA, Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)
Clone
162 33 D3
Formulation
In PBS, pH 7.4.
Immunogen
5-methylcytosine conjugated to ovalbumin
Regulatory Status
RUO
Test Specificity
Recognizes 5-methylcytosine in methylated DNA or RNA in NIH3T3 cells. Affinity purified mouse monoclonal antibody. Detects methylated DNA from a broad range of species.
Content And Storage
−20°C
Isotype
IgG1
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Description
- Specifically detects 5-Methylcytosine Clone: 162 33 D3 in Multi samples, and it is validated for ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmunoassay, Immuno Blotting DNA methylation plays an important role in gene regulation
- Methylation of gene-promoter regions leads to loss of function while DNA demethylation can lead to gain of function
- Alterations in DNA methylation may play an important role in carcinogenesis
- DNA methylation varies according to tissue type
- In some cancers types such as Wilms tumor and colon adenocarcinoma have a decrease in global DNA methylation
- In contrast other cancers such as breast cancer have DNA hypermethylation
- Changes in global DNA methylation status may be useful early markers for the detection of premalignant lesions.