Myogenin Antibody (F5D), FITC, Novus Biologicals™

Myogenin

Monoclonal

FITC

PBS with 0.05% Sodium Azide

MYOG

Rat Myogenin peptide (aa 73-94) followed by rat Myogenin recombinant fragment (aa30-224) (Epitope aa138-158) (Uniprot: P15173)

0.1 mL

Cancer, Stem Cell Markers, Transcription Factors and Regulators

Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.

Store at 4°C in the dark.

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

F5D

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

BHLHC3, bHLHc3Myogenic factor-4; myogenin, Class C basic helix-loop-helix protein 3, myf-4, MYF4myogenin, Myogenic factor 4, MYOGENIN, myogenin (myogenic factor 4)

Mouse

Protein A or G purified

RUO

Primary

Human, Mouse, Rat, Porcine, Feline

IgG1 κ