DOG1/TMEM16A Antibody (SPM580), FITC, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB006884-Each-of-1 | In Stock | ₹ 57,494.00 |
NB006884 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,494.00
GST (18%): ₹ 10,348.92
Total Price: ₹ 67,842.92
Antigen
DOG1/TMEM16A
Classification
Monoclonal
Conjugate
FITC
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
ANO1
Immunogen
Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)
Quantity
0.1 mL
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG1 κ
Applications
ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone
SPM580
Dilution
ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Test Specificity
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
Content And Storage
Store at 4°C in the dark.
Related Products
Description
- DOG1/TMEM16A Monoclonal specifically detects DOG1/TMEM16A in Human samples
- It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.