CDX2 Antibody (PCRP-CDX2-1A3), DyLight 405, Novus Biologicals™

CDX2

Monoclonal

DyLight 405

50mM Sodium Borate with 0.05% Sodium Azide

CDX2

Recombinant human full-length CDX2 protein (Uniprot: Q99626)

0.1 mL

Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators

The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Store at 4°C in the dark.

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

PCRP-CDX2-1A3

Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2

Mouse

Protein A or G purified

RUO

Primary

Human

IgG1 κ