MyoD Antibody (MYOD1/2075R), DyLight 488, Novus Biologicals™

MyoD

Monoclonal

DyLight 488

50mM Sodium Borate with 0.05% Sodium Azide

MYOD1

Recombinant human full-length MyoD protein (Uniprot: P15172 )

0.1 mL

Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific

Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.

Store at 4°C in the dark.

Immunohistochemistry, Immunohistochemistry (Paraffin)

MYOD1/2075R

Immunohistochemistry, Immunohistochemistry-Paraffin

bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM

Rabbit

Protein A purified

RUO

Primary

Human

IgG