CD63 Antibody (LAMP3/2788), DyLight 488, Novus Biologicals™

CD63

Monoclonal

DyLight 488

50mM Sodium Borate with 0.05% Sodium Azide

CD63

Recombinant human CD63 protein fragment (around aa100-197) (exact sequence is proprietary) (Uniprot: P08962 )

0.1 mL

Autophagy, Cancer, Cardiovascular Biology, Cytokine Research, Immunology, Innate Immunity, Lysosome Markers, Metastasis

This monoclonal antibody recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of monoclonal antibody LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak

Store at 4°C in the dark.

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

LAMP3/2788

Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

CD63 antigen, CD63 antigen (melanoma 1 antigen), CD63 molecule, Granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, ME491, melanoma 1 antigen, Melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1lysosome-associated membrane glycoprotein 3, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, tspan-30, TSPAN30granulophysin

Mouse

Protein A or G purified

RUO

Primary

Human, Mouse

IgG2b κ