Emerin Antibody (EMD/2167), HRP, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB012550-Each-of-1 | In Stock | ₹ 57,494.00 |
NB012550 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,494.00
GST (18%): ₹ 10,348.92
Total Price: ₹ 67,842.92
Antigen
Emerin
Classification
Monoclonal
Conjugate
HRP
Formulation
PBS with No Preservative
Gene Symbols
EMD
Immunogen
Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary) (Uniprot: P50402)
Quantity
0.1 mL
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG1 κ
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone
EMD/2167
Dilution
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias
emerin, Emery-Dreifuss muscular dystrophy, LEM domain containing 5, STAEDMDLEMD5
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Test Specificity
Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.
Content And Storage
Store at 4°C in the dark.
Related Products
Description
- Emerin Monoclonal specifically detects Emerin in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.