Endoglin/CD105, Rabbit anti-Mouse, Clone: MJ7/18, Novus Biologicals™

Endoglin/CD105

Monoclonal

1 mg/mL

Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation

CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1

Rabbit

Protein A purified

RUO

Primary

MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

IgG κ

Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation

MJ7/18

Unconjugated

PBS

ENG

MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.

0.2 mg

Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers

2022

Mouse

Purified