Cholera Toxin Beta Antibody - BSA Free, Novus Biologicals™

Cholera Toxin Beta

Polyclonal

Unconjugated

Phosphate buffered saline with 0.1% Sodium Azide

Rabbit

IgG purified

RUO

NB100-63067 is specific for the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. This antibody immunoprecipitates cholera toxin in gel techniques.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

IgG

ELISA, Immunodiffusion, Immunohistochemistry (Frozen)

4 mg/mL

ELISA 1:100-1:2000, Immunohistochemistry-Frozen, Immunodiffusion

Cholera enterotoxin B chain, Cholera enterotoxin beta chain, Cholera enterotoxin gamma chain, Cholera enterotoxin subunit B, Cholera toxin B protein, Choleragenoid, CTX B, CTXB, TOX B, toxB, VC1456

Purified choleragenoid

0.1 mL

Primary

Bacteria

Purified