TfR (Transferrin R) Antibody (TFRC/1818) - Azide and BSA Free, Novus Biologicals™

TfR (Transferrin R)

Monoclonal

1 mg/mL

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, CyTOF-ready

CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr

Mouse

Protein A or G purified

RUO

Primary

It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Store at -20 to -80C. Avoid freeze-thaw cycles.

IgG2b κ

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

TFRC/1818

Unconjugated

PBS with No Preservative

TFRC

Recombinant human extracellular TFRC protein fragment (aa94-212) (exact sequence is proprietary)

100 μg

Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers

7037

Human

Purified