CD3 epsilon Antibody (APA1/1), Alexa Fluor™ 700, Novus Biologicals™

CD3 epsilon

Monoclonal

Alexa Fluor 700

CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE

Mouse

Protein A purified

RUO

Primary

The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Store at 4C in the dark.

IgG1

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

APA1/1

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

CD3E

Purified human CD3 proteins isolated from thymus

0.1 mL

Adaptive Immunity, Apoptosis, Diabetes Research, Immunology, Innate Immunity, Signal Transduction

916

Human, Mouse

Purified