Cytochrome b245 alpha Antibody (CS9), DyLight 550, Novus Biologicals™

Cytochrome b245 alpha

Monoclonal

DyLight 550

50 mM sodium borate with 0.05% sodium azide

CYBA

Cytochrome B245 solubilised in octyl-beta-gluycopyranoside

0.1 mL

1535.0

Human

IgG1

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Frozen)

CS9

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Frozen

cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit

Mouse

Protein G purified

Primary

This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.

Store at 4°C in the dark.