MRP6 Antibody (M6II-7), Novus Biologicals™

MRP6

Monoclonal

Unconjugated

Anthracycline resistance-associated protein, ARAPXE, ATP-binding cassette, sub-family C (CFTR/MRP), member 6, EST349056, MLP1ABC34, MOATE, MOAT-E, MRP6ATP-binding cassette sub-family C member 6, multidrug resistance-associated protein 6, Multi-specific organic anion transporter E, pseudoxanthoma elasticum, PXE1, URG7

Rat

Tissue culture supernatant

RUO

Primary

M6II-7 reacts with MRP6, a 190-200 kD transmembrane protein that is related to the multidrug resistance related protein MRP. Mutations in the MRP6 gene are responsible for the connective tissue disorder Pseudoxanthoma elasticum (PXE). M6II-7 was raised against a bacterial fusion protein of human MRP6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein. M6II-7 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

IgG2 α

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

M6II-7

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

ABCC6

The antibody reacts with the MRP6 antigen.

0.2 mL

Cancer

368

Human

Supernatant