Cytochrome b245 alpha Antibody (CS9), Janelia Fluor™ 646, Novus Biologicals™

Cytochromeb245alpha

Monoclonal

Janelia Fluor 646

50mM Sodium Borate with 0.05% Sodium Azide

CYBA

Cytochrome B245 solubilised in octyl-beta-gluycopyranoside

0.1 mL

1535

Human

Purified

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

CS9

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit

Mouse

Protein G purified

Primary

This antibody recognizes the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterized by severe recurrent infections.

Store at 4°C in the dark.

IgG1