TAG-72 Antibody (CC49), Novus Biologicals™

TAG-72

Monoclonal

0.2mg/mL

Western Blot 1:200-1:400, Flow Cytometry 0.5ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 1:200-1:400, Immunohistochemistry-Frozen 1:200-1:400

CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Purified TAG-72 protein

Protein A purified

RUO

182875

Protein A purified

Store at 4C.

IgG1 κ

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

CC49

Unconjugated

PBS with 0.05% BSA. with 0.05% Sodium Azide

Mouse

220 kDa

0.1 mg

Primary

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Human, Rat, Bovine, Canine

Purified