Moesin Antibody (MSN/491), Novus Biologicals™

Moesin

Monoclonal

0.2 mg/ml

Western Blot 0.5-1 μg/mL, Simple Western 1.0 μg/mL, Flow Cytometry 0.5-1 μg/million cells, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 0.5-1 μg/mL, Immunoprecipitation 0.5-1 μg/500 μg protein lysate, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL, Immunohistochemistry-Frozen 0.5-1.0 μg/mL

Membrane-organizing extension spike protein, moesin

Mouse

Protein A or G purified

RUO

Primary

Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Store at 4C.

IgG1 κ

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

MSN/491

Unconjugated

P26038

MSN

Recombinant full-length human Moesin protein (Uniprot: P26038)

100 μg

Cytoskeleton Markers, Stem Cell Markers

4478

Human, Rat

Purified