NBP233054V

MALT1 Antibody (MT1/410), DyLight 405, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP233054V-Each-of-1 In Stock ₹ 57,494.00

NBP233054V - Each of 1

₹ 57,494.00

In Stock

Quantity

1

Base Price: ₹ 57,494.00

GST (18%): ₹ 10,348.92

Total Price: ₹ 67,842.92

Antigen

MALT1

Classification

Monoclonal

Conjugate

DyLight 405

Gene Alias

caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

ELISA

Clone

MT1/410

Dilution

ELISA

Gene Symbols

MALT1

Immunogen

Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Tumor Suppressors

Gene ID (Entrez)

10892

Target Species

Human

Form

Purified

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Description

  • MALT1 Monoclonal specifically detects MALT1 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.