EBV Early Antigens Antibody (1108-1), Alexa Fluor™ 405, Novus Biologicals™

EBV Early Antigens

Monoclonal

Alexa Fluor 405

Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera

0.1 mL

Primary

Virus

Purified

Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

1108-1

Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Mouse

Protein A or G purified

RUO

Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Store at 4C in the dark.

IgG1 κ