c-Myb Antibody (MYB286), HRP, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP234690H-Each-of-1 | In Stock | ₹ 57,494.00 |
NBP234690H - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,494.00
GST (18%): ₹ 10,348.92
Total Price: ₹ 67,842.92
Antigen
c-Myb
Classification
Monoclonal
Conjugate
HRP
Gene Alias
c-myb, Cmyb, c-myb protein (140 AA), c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, Proto-oncogene c-Myb, transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog (avian)
Host Species
Mouse
Molecular Weight of Antigen
75 kDa
Quantity
0.1 mL
Research Discipline
Cancer
Gene ID (Entrez)
4602
Target Species
Human
Form
Purified
Applications
Western Blot, ELISA
Clone
MYB286
Dilution
Western Blot, ELISA
Gene Symbols
MYB
Immunogen
A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein, coupled to KLH (Uniprot: P01104)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Related Products
Description
- c-Myb Monoclonal specifically detects c-Myb in Human samples
- It is validated for ELISA.