MUC5AC Antibody (SPM297), Alexa Fluor™ 488, Novus Biologicals™

Mucin 5AC

Monoclonal

Alexa Fluor 488

gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin

Mouse

Protein A or G purified

RUO

Primary

This monoclonal antibody recognizes the peptide core of gastric mucin M1 (1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.

Store at 4C in the dark.

IgG1 κ

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

SPM297

Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

MUC5AC

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

0.1 mL

Cellular Markers, Extracellular Matrix, Infections (Virus Bacteria and Parasites), Signal Transduction

4586

Human, Mouse, Rat, Porcine, Chicken, Feline, Monkey, Rabbit, Bovine (Negative)

Purified