Von Willebrand Factor Antibody (SPM577), HRP, Novus Biologicals™

Von Willebrand Factor

Monoclonal

HRP

coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF

Mouse

250 kDa

0.1 mL

Cancer

7450

Human

Purified

Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoprecipitation

SPM577

Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

VWF

Recombinant human Von Willebrand Factor fragment (Uniprot: P04275 )

Protein A or G purified

RUO

Primary

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Store at 4C in the dark.

IgG1 κ