Moesin Antibody (MSN/492), Novus Biologicals™

Moesin

Monoclonal

0.2mg/mL

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

P26038

MSN

Recombinant full-length human Moesin protein

Protein A or G purified

RUO

Primary

Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Store at 4C.

IgG1 κ

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

MSN/492

Unconjugated

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Membrane-organizing extension spike protein, moesin

Mouse

78 kDa

0.02 mg

Cytoskeleton Markers, Stem Cell Markers

4478

Human, Rat (Negative)

Purified