Insulin Antibody (IRDN/805), Novus Biologicals™

Insulin

Monoclonal

0.2mg/mL

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml

P01308

INS

Recombinant INS protein

Protein A or G purified

RUO

Primary

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Store at 4C.

IgG1 κ

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

IRDN/805

Unconjugated

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Mouse

6 kDa

0.02 mg

Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

3630

Human, Mouse, Porcine, Primate, Rabbit, Rat (Negative)

Purified