NBP247836B

Ornithine Decarboxylase Antibody (ODC1/486) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Ornithine Decarboxylase

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.25 - 0.5 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias

ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1

Host Species

Mouse

Molecular Weight of Antigen

53 kDa

Quantity

0.2 mg

Research Discipline

Cell Cycle and Replication

Gene ID (Entrez)

4953

Target Species

Human, Rat

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone

ODC1/486

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Gene Symbols

ODC1

Immunogen

Recombinant human ODC-1 protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG2a κ

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Description

  • Description Ornithine Decarboxylase Monoclonal specifically detects Ornithine Decarboxylase in Human, Mouse, Rat samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.