NBP247984B

Cytokeratin 18 Antibody (KRT18/1190) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Cytokeratin 18

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias

Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18

Host Species

Mouse

Molecular Weight of Antigen

45 kDa

Quantity

0.2 mg

Research Discipline

Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers

Gene ID (Entrez)

3875

Target Species

Human, Rat

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone

KRT18/1190

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Gene Symbols

KRT18

Immunogen

Recombinant human KRT18 protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG1 κ

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Description

  • Cytokeratin 18 Monoclonal specifically detects Cytokeratin 18 in Human, Rat samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.