gp96/HSP90B1/GRP94 Antibody (HSP90B1/1192) - IHC-Prediluted, Novus Biologicals™

gp96/HSP90B1/GRP94

Monoclonal

Unconjugated

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

HSP90B1

Recombinant full-length human gp96/HSP90B1/GRP94 protein (Uniprot: P14625)

Protein A or G purified

RUO

Primary

Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This monoclonal antibody is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Store at 4C.

IgG2a κ

Immunohistochemistry (Paraffin)

HSP90B1/1192

Immunohistochemistry-Paraffin

94 kDa glucose-regulated protein, endothelial cell (HBMEC) glycoprotein, glucose regulated protein, 94 kDa, GP96ECGP, GRP-94, GRP94gp96 homolog, Heat shock protein 90 kDa beta member 1, heat shock protein 90kDa beta (Grp94), member 1, TRA1endoplasmin, tumor rejection antigen (gp96) 1, Tumor rejection antigen 1, Tumor rejection antigen-1 (gp96)

Rat

94 kDa

7 mL

Cancer, Cellular Markers, ER Markers, Golgi Apparatus Markers, Hypoxia, Membrane Trafficking and Chaperones

7184

Human

Purified