Involucrin Antibody (IVRN/827) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248274-Each-of-1 | In Stock | ₹ 46,636.00 |
NBP248274 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,636.00
GST (18%): ₹ 8,394.48
Total Price: ₹ 55,030.48
Antigen
Involucrin
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
IVL
Immunogen
Purified involucrin from human keratinocytes (Uniprot: P07476)
Quantity
7 mL
Research Discipline
Extracellular Matrix
Gene ID (Entrez)
3713
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
IVRN/827
Dilution
Immunohistochemistry-Paraffin
Gene Alias
involucrin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
It recognizes a protein of 66kDa-170kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this monoclonal antibody reacts with a 120kDa protein. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal; expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Involucrin Monoclonal specifically detects Involucrin in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.