MCM7 Mouse anti-Human, Clone: MCM7/1467, Novus Biologicals™

MCM7

Monoclonal

0.2 mg/mL

Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000

CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 3.6.4.12, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47

Mouse

88 kDa

20 μg

Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers

4176

Human

Purified

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), SDS-Page

MCM7/1467

Unconjugated

0mM PBS with 0.05% BSA with 0.05% Sodium Azide

MCM7

Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)

Protein A or G purified

RUO

Primary

The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

IgG2a κ