GP2 Antibody (GP2/1803) - Azide and BSA Free, Novus Biologicals™

GP2

Monoclonal

0.2 mg/ml

ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml

P55259

GP2

Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary) (Uniprot: P55259)

Protein A or G purified

Primary

GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

Store at 4°C.

IgG2a κ

ELISA, Immunohistochemistry (Paraffin)

GP2/1803

Unconjugated

10mM PBS with 0.05% BSA with 0.05% Sodium Azide

DKFZp779K0533, glycoprotein 2 (zymogen granule membrane), pancreatic secretory granule membrane major glycoprotein GP2, pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75

Mouse

59 kDa

100 μg

2813.0

Human

Purified