DC-SIGNR/CD299/CLEC4M Antibody (16E7), Alexa Fluor™ 532 - Chimeric, Novus Biologicals™

DC-SIGNR/CD299/CLEC4M

Monoclonal

Alexa Fluor 532

50 mM sodium borate with 0.05% sodium azide

CLEC4M

CD299

0.1 mL

Primary

Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.

Store at 4°C in the dark.

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence

160000000

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunofluorescence

CD209L1, CD209Ldendritic cell-specific ICAM-3-grabbing nonintegrin 2, CD299, CD299 antigenMGC129964, C-type lectin domain family 4, member M, DC-SIGN2CD209 antigen-like protein 1, DC-SIGNRDC-SIGN-related protein, DCSIGNRMGC47866, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, HP10347, liver/lymph node-specific ICAM-3 grabbing non-integrin, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN, LSIGNC-type lectin domain family 4 member M, mannose binding C-type lectin DC-SIGNR

Rabbit

Protein A or G purified

Adaptive Immunity, Immunology, Signal Transduction, Virology Bacteria and Parasites

10332.0

Human

IgG κ