NP233080A94

CD35 Antibody (E11), Alexa Fluor™ 594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP233080A94-Each-of-1 In Stock ₹ 57,494.00

NP233080A94 - Each of 1

₹ 57,494.00

In Stock

Quantity

1

Base Price: ₹ 57,494.00

GST (18%): ₹ 10,348.92

Total Price: ₹ 67,842.92

Antigen

CD35

Classification

Monoclonal

Conjugate

Alexa Fluor 594

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

CR1

Immunogen

Intact human monocytes were used as immunogen to generate the CD35 antibody (Hogg et al, 1984).

Quantity

0.1 mL

Gene ID (Entrez)

1378

Target Species

Human, Monkey

Isotype

IgG1 κ

Applications

ELISA

Clone

E11

Dilution

ELISA

Gene Alias

complement component (3b/4b) receptor 1 (Knops blood group), KN

Host Species

Mouse

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This monoclonal antibody is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This monoclonal antibody is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This monoclonal antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.

Content And Storage

Store at 4°C in the dark.

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Description

  • CD35 Monoclonal specifically detects CD35 in Human, Monkey, Baboon, Cynomolgus Monkey, Rhesus Macaque samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.